short interfering RNA

См. также в других словарях:

• Small interfering RNA — (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of 20 25 nucleotide long double stranded RNA molecules that play a variety of roles in biology. Most notably, siRNA is involved in the RNA interference (RNAi) pathway …   Wikipedia

• Short hairpin RNA — Unter RNA Interferenz (RNAi, auch RNA Silencing) versteht man einen natürlichen Mechanismus in eukaryotischen Zellen, der die Genexpression einzelner Gene hemmt. Bei dieser Genregulation ist immer RNA als zielerkennendes Molekül beteiligt. Nach… …   Deutsch Wikipedia

• RNA interference — (RNAi) is a mechanism that inhibits gene expression at the stage of translation or by hindering the transcription of specific genes. RNAi targets include RNA from viruses and transposons (significant for some forms of innate immune response), and …   Wikipedia

• RNA-induced silencing complex — RNA induced silencing complex, or RISC, is a multi protein siRNA complex which cleaves (incoming viral) dsRNA and binds short antisense RNA strands which are then able to bind complementary strands. When it finds the complementary strand, it… …   Wikipedia

• RNA-induced transcriptional silencing — (RITS) is a form of RNA interference by which short RNA molecules such as small interfering RNA (siRNA) trigger the downregulation of transcription of a particular gene or genomic region. This is usually accomplished by posttranslational… …   Wikipedia

• RNA — For other uses, see RNA (disambiguation). A hairpin loop from a pre mRNA. Highlighted are the nucleobases (green) and the ribose phosphate backbone (blue). Ribonucleic acid (English pronunciation: /raɪbɵ.njuːˌkleɪ.ɨk ˈæsɪd/), or RNA, is one of… …   Wikipedia

• RNA-Interferenz — Übergeordnet Gen Silencing Post Transkriptionelles Gen Silencing Gene Ontology …   Deutsch Wikipedia

• Long non-coding RNA — Long noncoding RNAs (long ncRNAs) are generally considered (somewhat arbitrarily) as non protein coding transcripts longer than 200 nucleotides. This limit is due to practical considerations including the separation of RNAs in common experimental …   Wikipedia

• Messenger RNA — The life cycle of an mRNA in a eukaryotic cell. RNA is transcribed in the nucleus; processed, it is transported to the cytoplasm and translated by the ribosome. At the end of its life, the mRNA is degraded. Messenger RNA (mRNA) is a molecule of… …   Wikipedia

• Small hairpin RNA — A small hairpin RNA or short hairpin RNA (shRNA) is a sequence of RNA that makes a tight hairpin turn that can be used to silence gene expression via RNA interference. shRNA uses a vector introduced into cells and utilizes the U6 promoter to… …   Wikipedia

• Piwi-interacting RNA — (piRNA) is a class of small RNA molecules that is expressed in mammalian testes and somatic cells and forms RNA protein complexes with Piwi proteins. These piRNA complexes (piRCs) have been linked to transcriptional gene silencing of… …   Wikipedia